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Artificial insemination (IVF & ICSI)
overcomes high hurdles on the
the way to a desired child

Fertilisation outside the body 

This option is suitable if the fallopian tubes are severely blocked, or the sperm quality is severely limited.

 

 

A happy conclusion from the laboratory: IVF (in-vitro fertilisation) and ICSI (intracytoplasmic sperm injection)

 

In vitro fertilisation (IVF) has been used successfully for 40 years. Over eight million children have been born using this method, and half a million more are born every year. During in-vitro fertilisation, the fertilisation of the egg takes place in a test tube, rather than in the female body. The egg and the sperm must achieve fertilisation in the test tube itself.

BWith an intracytoplasmic injection (ICSI), we are able to help a little more: a single sperm cell is injected with a very fine needle, directly into an egg cell that has been removed from the woman’s ovary.

These two types of artificial insemination are suitable for:

  • Women with tubal blockage
  • Men with insufficient sperm production
  • Couples who have already gone through several inseminations without success
  • Couples who have been struggling to conceive a child for an extended period of time

 

 

„How does artificial insemination with IVF and ICSI work exactly?“

 

  1. We stimulate the ovary in order for several eggs to mature.

    RIf not just one, but several eggs mature in the cycle, the chance of finding the right eggs for pregnancy increases, and with it, the chance of getting pregnant within that cycle.

    The stimulation hormones (gonadotropins) are administered in the form of injections. The patient or couple can usually self-administer these - you would receive precise injection instructions for this at the beginning of your therapy.

     
  2. We remove the mature follicle out of the ovary.

    We take the follicle out of the ovary with a very fine needle. The eggs are then removed from the fluid under a microscope and prepared for the appropriate procedure of artificial insemination.

    FWe recommend a light anaesthetic for our patients. There may be a small amount of bleeding and lower abdominal discomfort afterwards. This is completely normal - not to mention harmless - and will cease after a few days.
     
  3. The egg is fertilised in the laboratory

    The retrieved eggs are now combined with the partner’s or donor’s sperm in the laboratory. In order for this to be successful, we require a fresh sample produced on the day of the procedure or a previously obtained frozen sample.
  • Fertilisation in the “conventional” way (IVF)

    If the quality is suitable, then the sperm are prepared and combined with the eggs in a nutrient solution. In the incubator, “almost natural” fertilisation takes place - the sperm cells independently penetrate the eggs. However, this requires a sufficient number of sperm cells (approx. 30,000 per egg cell) as well as good mobility.
     

  • Artificial Insemination (ICSI)

    If the number or quality of the sperm cells is limited, we recommend the ICSI method (intracytoplasmic sperm injection). The reproductive biologists select the most suitable sperm under a high-resolution microscope and inject it directly into the egg.

With both techniques, the presence of the sperm in the mature egg triggers the fertilisation process, which is checked under the microscope the following day.

 

 

 

Fertilisation without hormone stimulation (“mini-IVF” or “natural cycle IVF”)

 

In recent years, the term “less is more” has become more and more applicable to fertility treatments. In our practice we use hormone stimulation with caution, as a result of the possible side effects or risks for the patient.

 

Thanks to the latest medical technology - the Time-Lapse Incubator (Geri, Merck) - it is possible to transfer single embryos without compromising a successful treatment, and thus reducing the risk of multiple pregnancies.

 

Despite needing the help of artificial insemination, for example in the case of blocked fallopian tubes, some women want a therapy that is as “natural” as possible, without having hormone stimulation. Therefore, provided there are no cycle disorders, we offer egg fertilisation in the laboratory without stimulation (natural cycle IVF). During this so-called “natural” IVF, we wait for the regular course of the cycle until the egg follicle has matured sufficiently. We then induce ovulation (adding a small amount of hormones) in order to increase the chance of obtaining a mature egg cell during the puncture. You can find out more about natural IVF at our information evenings or alternatively through the IVF-Naturelle Kompetenznetz (Natural IVF Competence Network), of which we are a member.

 

It is noteworthy that the first IVF treatments 40 years ago worked without stimulation. At the time, the necessary drugs did not exist.

 

 

 

The baby moves into the uterus (embryo transfer)

Once a multicellular embryo has developed from the fertilised egg after several days, we insert it into the patient’s uterus with the help of a thin catheter. It will embed here, and the pregnancy can begin. The insertion of the fertilised egg is painless and therefore takes place without anaesthesia. Once the egg is in the mother’s body, resting further is not necessary and does not improve the probability of pregnancy.

 

 

 

What are the chances of my wish for a child becoming a reality?

It is very understandable that this question is of particular concern to our patients. IVF treatment is considered successful if pregnancy occurs after the embryo transfer. In our Wunschkinder practice, the pregnancy rate is > 40%. After three IVF/ICSI treatments, the cumulative pregnancy rate is at 70% worldwide.

This means that after three embryo transfers, more than every second woman becomes pregnant!

 

 

 

Are my chances higher abroad?

Fertility centres, particularly in neighbouring countries, often advertise pregnancy rates of 60% per treatment. Most suggest that more is possible in these countries than in Germany. However, we advise you to be cautious with these figures: often the pregnancy rates are counted differently and may not necessarily be more successful. A rate of 60% per treatment is not biologically possible. Often many embryos are transferred abroad, which can lead to multiple pregnancies (triplets, quadruplets etc.) that can be dangerous for mother and child.

 

 

 

Obtaining sperm for the child you want - a real challenge for your partner

Insemination treatment and artificial insemination outside of the body have one thing in common: on the day of ovulation or egg retrieval, fresh semen is needed from your partner for fertilisation, which can be best produced in our practice. If this is not possible for professional or other reasons, we can also offer to freeze the sperm in advance. Understandably, many men find 50 it difficult to provide the necessary semen at a precise time with the help of masturbation. Talk to us if there are any issues and we will be happy to advise you.

 

 

Learn more about artificial insemination as a fertility treatment

We regularly offer information evenings about artificial insemination on the first and third Thursday of every month at 6:30 pm. You can secure a place by calling 030880349056, or by sending a short message via email to info@wunschkinder-berlin.de. Would you like a personal appointment? You can make an appointment on our booking site. Sie wünschen einen persönlichen Arzttermin? Treffen Sie Ihre Terminwahl auf unserer Reservierungseite.

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